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Marumerizer Spheronizer

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  • Operation

  • Features and Benefits

  • Literature

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Operation

The Marumerizer™ spheronizer from LCI, manufactured by Fuji Paudal, produces smooth, uniform spheres (pharmaceutical beads).

The feed material to the spheronizer can be extruded particles or moist granules from a mixer/granulator. Since an extruded particle has at least two dimensions already defined, a narrow final particle size distribution is possible.

Particles are fed onto the spinning friction plate, which throws them against the inside wall of the cylinder. Extruded particles are quickly broken into segments approximately one diameter long. Centrifugal and gravitational forces create a mechanically fluidized ring of particles. Collisions with the wall, friction plate and other particles result in the plastic deformation of each granule, quickly creating a spherical shape. The desired shape for a specific application is time and formulation dependent and is achieved, predictably and repeatedly, in a brief period called the "spheronization time".

Features and Benefits

Spheronization improves your product's performance by:

  • Producing a smooth particle surface suitable for thin layer coating
  • Forming granules with a specific bio-consumable shape
  • Conditioning particles to prevent generation of dust and fines from usage or shipping
  • Increasing flowability by elimination of sticking or bridging points
  • Increasing the apparent bulk density up to 25% compared to extruded material
spheronization results

Literature

Related Products

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